映画『銀河ヒッチハイク・ガイド』のオリジナル・サウンドトラックは、2004年７月から2005年３月14日までかけて録音され、ＣＤは2005年４月にHollywood Records から発売された。なお、*のついている曲は映画の中では実際に使用されていない。
また、"So Long & Thanks for All the Fish" は、第78回アカデミー賞オリジナル歌曲賞のノミネート曲を選ぶための42曲のうちの１曲には入ったが、ノミネートには至らなかった。
| 01 | The Dolphins | 1:00 |
| 02 | So Long & Thanks for All the Fish | 2:26 |
| Hilary Summers, Kemi Ominiyi & The R'svp Voices | ||
| 03 | Arthur Wakes Up | 2:53 |
| 04 | Shoo-Rah! Shoo-Rah! | 2:51 |
| Betty Wright | ||
| 05 | Here I Am (Come and Take Me) | 4:13 |
| Al Green | ||
| 06 | Destruction of Earth | 1:31 |
| 07 | Journey of the Sorcerer | 1:15 |
| 08 | The Hitchhiker's Guide to the Galaxy | 1:14 |
| 09 | Inside the Vogon Ship | 2:46 |
| 10 | Vogon Poetry | 0:48 |
| 11 | Space | 1:00 |
| 12 | Vogon Command Centre | 1:00 |
| 13 | Trillian & Arthur Reunited | 1:45 |
| 14 | Pan Galactic Gargle Blaster | 1:40 |
| 15 | Tea in Space | 1:08 |
| 16 | Deep Thought | 2:06 |
| 17 | Infinite Improbability Drive | 0:55 |
| 18 | Viltvodle Street Music | 0:45 |
| 19 | Huma's Hymn | 1:02 |
| 20 | Capture of Trillian | 4:27 |
| 21 | Vogcity | 1:02 |
| 22 | Love | 1:44 |
| 23 | The Whale | 1:53 |
| 24 | Planet Factory Floor | 2:29 |
| 25 | Earth Mark II | 6:29 |
| 26 | Magic Moments | 2:37 |
| 27 | Shootout | 3:23 |
| 28 | Finale | 1:50 |
| 29 | Blast Off | 0:16 |
| 30 | So Long & Thanks for All the Fish (Reprise) | 2:54 |
| Neil Hannon | ||
| 31 | Careless Talk | 1:42 |
| 32 | Vote Beeblebrox* | 3:27 |
| Andy Dunlop, Chuck Norman, Douglas Payne, Fran Balke, Hannah Thomas, Miggy Barradas & Neil Hannon | ||
| 33 | Reasons to Be Miserable (His Name Is Marvin)* | 3:37 |
| Stephen Fry |
Score Written & Produced by Joby Talbot
Except tracks 2 & 30 Written by Joby Talbot, Garth Jennings & Christopher Austin,
& track 7 Written by Bernie LeadonOrchestrations by Christopher Austin except track7 by Joby Talbot & track 22 by Gary Carpneter
Score Recorded & Mixed by Nigel Godrich & Dan Grech-Marguerat
Assistant Engineers - Nick Cervonaro & Jack Jackson
Music Editor - Michael Connell
Conductor - Christopher Austin
Orchestral Conductor - Isobel Griffiths
Representation - Manners McDate Artist ManagementRecorded at: Air, Abbey Road, Rak & Mark Angelo Studios
Mastered by Mark Wyllie at Sanctuary Town House, London
Assistant Engineer: Daniel Porter
So Long & Thanks for All the Fish （参考）
So long, and thanks for all the fish
So sad that it should come to this
We tried to warn you all
but oh dear
You may not share out intellect
Which might explain your disrespect
For all the natural wonders that
grow around you
So long so long and thanks
for all the fish!The world's about to be destroyed
There's no point getting all annoyed
Lie back and let the planet
dissolve around you
Despite those nets of tuna fleets
We thought that most of you were sweet
Especially tiny tots
and your pregnant womenSo long so long
So long so long so long
So long so long
So long so long so long
So long so long and thanks
for all the fishIf I had just one last wish
I would like a tasty fish
If we could just change one thing
We would all have lungs to sing
Come one and all
Man and mammal
Side by side in
Life's great gene poolOoh ooh
Ah ahSo long so long
So long so long so long
So long so long
So long so long so long
So long so long and thanks
for all the fish